Vacuolar targeting of recombinant antibodies in Nicotiana benthamiana
نویسندگان
چکیده
منابع مشابه
Vacuolar targeting of recombinant antibodies in Nicotiana benthamiana
Plant-based platforms are extensively used for the expression of recombinant proteins, including monoclonal antibodies. However, to harness the approach effectively and leverage it to its full potential, a better understanding of intracellular processes that affect protein properties is required. In this work, we examined vacuolar (vac) targeting and deposition of the monoclonal antibody (Ab) 1...
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The expression of clinically useful proteins in plants has been bolstered by the development of high-yielding systems for transient protein expression using agroinfiltration. There is a need now to know more about how host plant development and metabolism influence the quantity and quality of recombinant proteins. Endogenous proteolysis is a key determinant of the stability and yield of recombi...
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ژورنال
عنوان ژورنال: Plant Biotechnology Journal
سال: 2016
ISSN: 1467-7644,1467-7652
DOI: 10.1111/pbi.12580